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Publications

See a complete list of Dr. Adrian Piliponsky’s publications on PubMed.

  

  • Neutrophilic asthma at an inhibitory checkpoint: A PD-1-targeted approach.

    Samanas NB, Murphy RC, Miralda I, Hallstrand TS, Piliponsky AM

    36463980 The Journal of allergy and clinical immunology , 2023 Feb.: 151 (2 ) 420-422

  • Single-cell analysis identifies the interaction of altered renal tubules with basophils orchestrating kidney fibrosis.

    Doke T, Abedini A, Aldridge DL, Yang YW, Park J, Hernandez CM, Balzer MS, Shrestra R, Coppock G, Rico JMI, Han SY, Kim J, Xin S, Piliponsky AM, Angelozzi M, Lefebvre V, Siracusa MC, Hunter CA, Susztak K

    35552540 Nature immunology , 2022 June: 23 (6 ) 947-959

  • Mast cell surfaceome characterization reveals CD98 heavy chain is critical for optimal cell function.

    Saha SS, Samanas NB, Miralda I, Shubin NJ, Niino K, Bhise G, Acharya M, Seo AJ, Camp N, Deutsch GH, James RG, Piliponsky AM

    34324892 The Journal of allergy and clinical immunology , 2022 Feb.: 149 (2 ) 685-697 PMCID: PMC8792104

  • Location of eosinophils in the airway wall is critical for specific features of airway hyperresponsiveness and T2 inflammation in asthma.

    Al-Shaikhly T, Murphy RC, Parker A, Lai Y, Altman MC, Larmore M, Altemeier WA, Frevert CW, Debley JS, Piliponsky AM, Ziegler SF, Peters MC, Hallstrand TS

    35027395 The European respiratory journal , 2022 Jan 13

  • The Autoimmune Risk R262W Variant of the Adaptor SH2B3 Improves Survival in Sepsis.

    Allenspach EJ, Shubin NJ, Cerosaletti K, Mikacenic C, Gorman JA, MacQuivey MA, Rosen ABI, Timms AE, Wray-Dutra MN, Niino K, Liggitt D, Wurfel MM, Buckner JH, Piliponsky AM, Rawlings DJ

    34740959 Journal of immunology (Baltimore, Md. : 1950) , 2021 Dec 1: 207 (11 ) 2710-2719 PMCID: PMC8612972

  • Spiny mice activate unique transcriptional programs after severe kidney injury regenerating organ function without fibrosis.

    Okamura DM, Brewer CM, Wakenight P, Bahrami N, Bernardi K, Tran A, Olson J, Shi X, Yeh SY, Piliponsky A, Collins SJ, Nguyen ED, Timms AE, MacDonald JW, Bammler TK, Nelson BR, Millen KJ, Beier DR, Majesky MW

    34849462 iScience , 2021 Nov 19: 24 (11 ) 103269 PMCID: PMC8609232

  • Effects of Asthma and Human Rhinovirus A16 on the Expression of SARS-CoV-2 Entry Factors in Human Airway Epithelium.

    Murphy RC, Lai Y, Barrow KA, Hamerman JA, Lacy-Hulbert A, Piliponsky AM, Ziegler SF, Altemeier WA, Debley JS, Gharib SA, Hallstrand TS

    32946274 American journal of respiratory cell and molecular biology , 2020 Dec.: 63 (6 ) 859-863 PMCID: PMC7790138

  • Thymic stromal lymphopoietin protects in a model of airway damage and inflammation via regulation of caspase-1 activity and apoptosis inhibition.

    Shubin NJ, Clauson M, Niino K, Kasprzak V, Tsuha A, Guga E, Bhise G, Acharya M, Snyder JM, Debley JS, Ziegler SF, Piliponsky AM

    32103153 Mucosal immunology , 2020 July: 13 (4 ) 584-594 PMCID: PMC7312418

  • Serum Protein Changes in Pediatric Sepsis Patients Identified With an Aptamer-Based Multiplexed Proteomic Approach.

    Shubin NJ, Navalkar K, Sampson D, Yager TD, Cermelli S, Seldon T, Sullivan E, Zimmerman JJ, Permut LC, Piliponsky AM

    31714400 Critical care medicine , 2020 Jan.: 48 (1 ) e48-e57

  • Adoptive Transfer of Basophils Enriched from Mouse Spleen.

    Piliponsky AM, Galli SJ

    33654915 Bio-protocol , 2019 Nov 5: 9 (21 ) e3416 PMCID: PMC7853924

  • Airway epithelium-shifted mast cell infiltration regulates asthmatic inflammation via IL-33 signaling.

    Altman MC, Lai Y, Nolin JD, Long S, Chen CC, Piliponsky AM, Altemeier WA, Larmore M, Frevert CW, Mulligan MS, Ziegler SF, Debley JS, Peters MC, Hallstrand TS

    31437129 The Journal of clinical investigation , 2019 Nov 1: 129 (11 ) 4979-4991 PMCID: PMC6819127

  • Mast Cells in Viral, Bacterial, and Fungal Infection Immunity.

    Piliponsky AM, Acharya M, Shubin NJ

    31212724 International journal of molecular sciences , 2019 Jun 12: 20 (12 ) PMCID: PMC6627964

  • Basophil-derived tumor necrosis factor can enhance survival in a sepsis model in mice.

    Piliponsky AM, Shubin NJ, Lahiri AK, Truong P, Clauson M, Niino K, Tsuha AL, Nedospasov SA, Karasuyama H, Reber LL, Tsai M, Mukai K, Galli SJ

    30664762 Nature immunology , 2019 Feb.: 20 (2 ) 129-140 PMCID: PMC6352314

  • Respiratory Syncytial Virus Infection of Human Lung Fibroblasts Induces a Hyaluronan-Enriched Extracellular Matrix That Binds Mast Cells and Enhances Expression of Mast Cell Proteases.

    Reeves SR, Barrow KA, Rich LM, White MP, Shubin NJ, Chan CK, Kang I, Ziegler SF, Piliponsky AM, Wight TN, Debley JS

    32047499 Frontiers in immunology , 2019: 10 3159 PMCID: PMC6997473

  • Mast cell chymase decreases the severity of group B Streptococcus infections.

    Gendrin C, Shubin NJ, Boldenow E, Merillat S, Clauson M, Power D, Doran KS, Abrink M, Pejler G, Rajagopal L, Piliponsky AM

    28916188 The Journal of allergy and clinical immunology , 2018 July: 142 (1 ) 120-129.e6 PMCID: PMC5847414

  • The contribution of mast cells to bacterial and fungal infection immunity.

    Piliponsky AM, Romani L

    29431211 Immunological reviews , 2018 March: 282 (1 ) 188-197 PMCID: PMC5812373

  • Secreted PLA2 group X orchestrates innate and adaptive immune responses to inhaled allergen.

    Nolin JD, Lai Y, Ogden HL, Manicone AM, Murphy RC, An D, Frevert CW, Ghomashchi F, Naika GS, Gelb MH, Gauvreau GM, Piliponsky AM, Altemeier WA, Hallstrand TS

    29093264 JCI insight , 2017 Nov 2: 2 (21 ) PMCID: PMC5752296

  • Proteome analysis of mast cell releasates reveals a role for chymase in the regulation of coagulation factor XIIIA levels via proteolytic degradation.

    Shubin NJ, Glukhova VA, Clauson M, Truong P, Abrink M, Pejler G, White NJ, Deutsch GH, Reeves SR, Vaisar T, James RG, Piliponsky AM

    27302551 The Journal of allergy and clinical immunology , 2017 Jan.: 139 (1 ) 323-334 PMCID: PMC5107356

  • Thymic Stromal Lymphopoietin Improves Survival and Reduces Inflammation in Sepsis.

    Piliponsky AM, Lahiri A, Truong P, Clauson M, Shubin NJ, Han H, Ziegler SF

    26934097 American journal of respiratory cell and molecular biology , 2016 Aug.: 55 (2 ) 264-74 PMCID: PMC4979369

  • Mast cell degranulation by a hemolytic lipid toxin decreases GBS colonization and infection.

    Gendrin C, Vornhagen J, Ngo L, Whidbey C, Boldenow E, Santana-Ufret V, Clauson M, Burnside K, Galloway DP, Adams Waldorf KM, Piliponsky AM, Rajagopal L

    26425734 Science advances , 2015 Jul 17: 1 (6 ) e1400225 PMCID: PMC4584422

  • Increased density of intraepithelial mast cells in patients with exercise-induced bronchoconstriction regulated through epithelially derived thymic stromal lymphopoietin and IL-33.

    Lai Y, Altemeier WA, Vandree J, Piliponsky AM, Johnson B, Appel CL, Frevert CW, Hyde DM, Ziegler SF, Smith DE, Henderson WR Jr, Gelb MH, Hallstrand TS

    24220317 The Journal of allergy and clinical immunology , 2014 May: 133 (5 ) 1448-55 PMCID: PMC4004718

  • Mast cell anaphylatoxin receptor expression can enhance IgE-dependent skin inflammation in mice.

    Schäfer B, Piliponsky AM, Oka T, Song CH, Gerard NP, Gerard C, Tsai M, Kalesnikoff J, Galli SJ

    22728083 The Journal of allergy and clinical immunology , 2013 Feb.: 131 (2 ) 541-8.e1-9 PMCID: PMC3597773

  • Mast cell anaphylatoxin receptor expression can enhance IgE-dependent skin inflammation in mice.

    Schäfer B, Piliponsky AM, Oka T, Song CH, Gerard NP, Gerard C, Tsai M, Kalesnikoff J, Galli SJ

    22728083 The Journal of allergy and clinical immunology , 2013 Feb.: 131 (2 ) 541-8.e1-9 PMCID: PMC3597773

  • The chymase mouse mast cell protease 4 degrades TNF, limits inflammation, and promotes survival in a model of sepsis.

    Piliponsky AM, Chen CC, Rios EJ, Treuting PM, Lahiri A, Abrink M, Pejler G, Tsai M, Galli SJ

    22901752 The American journal of pathology , 2012 Sept.: 181 (3 ) 875-86 PMCID: PMC3432424

  • The chymase mouse mast cell protease 4 degrades TNF, limits inflammation, and promotes survival in a model of sepsis.

    Piliponsky AM, Chen CC, Rios EJ, Treuting PM, Lahiri A, Abrink M, Pejler G, Tsai M, Galli SJ

    22901752 The American journal of pathology , 2012 Sept.: 181 (3 ) 875-86 PMCID: PMC3432424

  • Reduced mast cell and basophil numbers and function in Cpa3-Cre; Mcl-1fl/fl mice.

    Lilla JN, Chen CC, Mukai K, BenBarak MJ, Franco CB, Kalesnikoff J, Yu M, Tsai M, Piliponsky AM, Galli SJ

    22001390 Blood , 2011 Dec 22: 118 (26 ) 6930-8 PMCID: PMC3245213

  • Reduced mast cell and basophil numbers and function in Cpa3-Cre; Mcl-1fl/fl mice.

    Lilla JN, Chen CC, Mukai K, BenBarak MJ, Franco CB, Kalesnikoff J, Yu M, Tsai M, Piliponsky AM, Galli SJ

    22001390 Blood , 2011 Dec.: 118 (26 ) 6930-8 PMCID: PMC3245213

  • Mast cell chymase reduces the toxicity of Gila monster venom, scorpion venom, and vasoactive intestinal polypeptide in mice.

    Akahoshi M, Song CH, Piliponsky AM, Metz M, Guzzetta A, Abrink M, Schlenner SM, Feyerabend TB, Rodewald HR, Pejler G, Tsai M, Galli SJ

    21926462 The Journal of clinical investigation , 2011 Oct.: 121 (10 ) 4180-91 PMCID: PMC3195461

  • Mast cell chymase reduces the toxicity of Gila monster venom, scorpion venom, and vasoactive intestinal polypeptide in mice.

    Akahoshi M, Song CH, Piliponsky AM, Metz M, Guzzetta A, Abrink M, Schlenner SM, Feyerabend TB, Rodewald HR, Pejler G, Tsai M, Galli SJ

    21926462 The Journal of clinical investigation , 2011 Oct.: 121 (10 ) 4180-91 PMCID: PMC3195461

  • Mast cell-derived TNF can exacerbate mortality during severe bacterial infections in C57BL/6-KitW-sh/W-sh mice.

    Piliponsky AM, Chen CC, Grimbaldeston MA, Burns-Guydish SM, Hardy J, Kalesnikoff J, Contag CH, Tsai M, Galli SJ

    20035049 The American journal of pathology , 2010 Feb.: 176 (2 ) 926-38 PMCID: PMC2808097

  • Mast cell-derived TNF can exacerbate mortality during severe bacterial infections in C57BL/6-KitW-sh/W-sh mice.

    Piliponsky AM, Chen CC, Grimbaldeston MA, Burns-Guydish SM, Hardy J, Kalesnikoff J, Contag CH, Tsai M, Galli SJ

    20035049 The American journal of pathology , 2010 Feb.: 176 (2 ) 926-38 PMCID: PMC2808097

  • Rabaptin-5 regulates receptor expression and functional activation in mast cells.

    Rios EJ, Piliponsky AM, Ra C, Kalesnikoff J, Galli SJ

    18698003 Blood , 2008 Nov 15: 112 (10 ) 4148-57 PMCID: PMC2582003

  • Rabaptin-5 regulates receptor expression and functional activation in mast cells.

    Rios EJ, Piliponsky AM, Ra C, Kalesnikoff J, Galli SJ

    18698003 Blood , 2008 Nov.: 112 (10 ) 4148-57 PMCID: PMC2582003

  • The development of allergic inflammation.

    Galli SJ, Tsai M, Piliponsky AM

    18650915 Nature , 2008 Jul 24: 454 (7203 ) 445-54 PMCID: PMC3573758

  • The development of allergic inflammation.

    Galli SJ, Tsai M, Piliponsky AM

    18650915 Nature , 2008 July: 454 (7203 ) 445-54 PMCID: PMC3573758

  • Neurotensin increases mortality and mast cells reduce neurotensin levels in a mouse model of sepsis.

    Piliponsky AM, Chen CC, Nishimura T, Metz M, Rios EJ, Dobner PR, Wada E, Wada K, Zacharias S, Mohanasundaram UM, Faix JD, Abrink M, Pejler G, Pearl RG, Tsai M, Galli SJ

    18376408 Nature medicine , 2008 April: 14 (4 ) 392-8 PMCID: PMC2873870

  • Neurotensin increases mortality and mast cells reduce neurotensin levels in a mouse model of sepsis.

    Piliponsky AM, Chen CC, Nishimura T, Metz M, Rios EJ, Dobner PR, Wada E, Wada K, Zacharias S, Mohanasundaram UM, Faix JD, Abrink M, Pejler G, Pearl RG, Tsai M, Galli SJ

    18376408 Nature medicine , 2008 April: 14 (4 ) 392-8 PMCID: PMC2873870

  • Mast cells in the promotion and limitation of chronic inflammation.

    Metz M, Grimbaldeston MA, Nakae S, Piliponsky AM, Tsai M, Galli SJ

    17498068 Immunological reviews , 2007 June: 217 304-28

  • Mast cells in the promotion and limitation of chronic inflammation.

    Metz M, Grimbaldeston MA, Nakae S, Piliponsky AM, Tsai M, Galli SJ

    17498068 Immunological reviews , 2007 June: 217 304-28

  • Thrombin-activatable procarboxypeptidase B regulates activated complement C5a in vivo.

    Nishimura T, Myles T, Piliponsky AM, Kao PN, Berry GJ, Leung LL

    17105819 Blood , 2007 Mar 1: 109 (5 ) 1992-7 PMCID: PMC1801069

  • Thrombin-activatable procarboxypeptidase B regulates activated complement C5a in vivo.

    Nishimura T, Myles T, Piliponsky AM, Kao PN, Berry GJ, Leung LL

    17105819 Blood , 2007 March: 109 (5 ) 1992-7 PMCID: PMC1801069

  • Mast cells can enhance resistance to snake and honeybee venoms.

    Metz M, Piliponsky AM, Chen CC, Lammel V, Abrink M, Pejler G, Tsai M, Galli SJ

    16873664 Science (New York, N.Y.) , 2006 Jul 28: 313 (5786 ) 526-30

  • Mast cells can enhance resistance to snake and honeybee venoms.

    Metz M, Piliponsky AM, Chen CC, Lammel V, Abrink M, Pejler G, Tsai M, Galli SJ

    16873664 Science (New York, N.Y.) , 2006 July: 313 (5786 ) 526-30

  • Human mast cells undergo TRAIL-induced apoptosis.

    Berent-Maoz B, Piliponsky AM, Daigle I, Simon HU, Levi-Schaffer F

    16455983 Journal of immunology (Baltimore, Md. : 1950) , 2006 Feb 15: 176 (4 ) 2272-8

  • Human mast cells undergo TRAIL-induced apoptosis.

    Berent-Maoz B, Piliponsky AM, Daigle I, Simon HU, Levi-Schaffer F

    16455983 Journal of immunology (Baltimore, Md. : 1950) , 2006 Feb.: 176 (4 ) 2272-8

  • The CC chemokine eotaxin/CCL11 has a selective profibrogenic effect on human lung fibroblasts.

    Puxeddu I, Bader R, Piliponsky AM, Reich R, Levi-Schaffer F, Berkman N

    16387592 The Journal of allergy and clinical immunology , 2006 Jan.: 117 (1 ) 103-10

  • The CC chemokine eotaxin/CCL11 has a selective profibrogenic effect on human lung fibroblasts.

    Puxeddu I, Bader R, Piliponsky AM, Reich R, Levi-Schaffer F, Berkman N

    16387592 The Journal of allergy and clinical immunology , 2006 Jan.: 117 (1 ) 103-10

  • Monomeric IgE enhances human mast cell chemokine production: IL-4 augments and dexamethasone suppresses the response.

    Matsuda K, Piliponsky AM, Iikura M, Nakae S, Wang EW, Dutta SM, Kawakami T, Tsai M, Galli SJ

    16337471 The Journal of allergy and clinical immunology , 2005 Dec.: 116 (6 ) 1357-63

  • Monomeric IgE enhances human mast cell chemokine production: IL-4 augments and dexamethasone suppresses the response.

    Matsuda K, Piliponsky AM, Iikura M, Nakae S, Wang EW, Dutta SM, Kawakami T, Tsai M, Galli SJ

    16337471 The Journal of allergy and clinical immunology , 2005 Dec.: 116 (6 ) 1357-63

  • Mast cell-deficient W-sash c-kit mutant Kit W-sh/W-sh mice as a model for investigating mast cell biology in vivo.

    Grimbaldeston MA, Chen CC, Piliponsky AM, Tsai M, Tam SY, Galli SJ

    16127161 The American journal of pathology , 2005 Sept.: 167 (3 ) 835-48 PMCID: PMC1698741

  • Mast cell-deficient W-sash c-kit mutant Kit W-sh/W-sh mice as a model for investigating mast cell biology in vivo.

    Grimbaldeston MA, Chen CC, Piliponsky AM, Tsai M, Tam SY, Galli SJ

    16127161 The American journal of pathology , 2005 Sept.: 167 (3 ) 835-48 PMCID: PMC1698741

  • Human peripheral blood eosinophils induce angiogenesis.

    Puxeddu I, Alian A, Piliponsky AM, Ribatti D, Panet A, Levi-Schaffer F

    15618019 The international journal of biochemistry & cell biology , 2005 March: 37 (3 ) 628-36

  • Human peripheral blood eosinophils induce angiogenesis.

    Puxeddu I, Alian A, Piliponsky AM, Ribatti D, Panet A, Levi-Schaffer F

    15618019 The international journal of biochemistry & cell biology , 2005 March: 37 (3 ) 628-36

  • Mast cells as "tunable" effector and immunoregulatory cells: recent advances.

    Galli SJ, Kalesnikoff J, Grimbaldeston MA, Piliponsky AM, Williams CM, Tsai M

    15771585 Annual review of immunology , 2005: 23 749-86

  • Mast cells as "tunable" effector and immunoregulatory cells: recent advances.

    Galli SJ, Kalesnikoff J, Grimbaldeston MA, Piliponsky AM, Williams CM, Tsai M

    15771585 Annual review of immunology , 2005: 23 749-86

  • Mast cells promote homeostasis by limiting endothelin-1-induced toxicity.

    Maurer M, Wedemeyer J, Metz M, Piliponsky AM, Weller K, Chatterjea D, Clouthier DE, Yanagisawa MM, Tsai M, Galli SJ

    15543132 Nature , 2004 Nov 25: 432 (7016 ) 512-6

  • Mast cells promote homeostasis by limiting endothelin-1-induced toxicity.

    Maurer M, Wedemeyer J, Metz M, Piliponsky AM, Weller K, Chatterjea D, Clouthier DE, Yanagisawa MM, Tsai M, Galli SJ

    15543132 Nature , 2004 Nov.: 432 (7016 ) 512-6

  • Tryptase, a novel link between allergic inflammation and fibrosis.

    Levi-Schaffer F, Piliponsky AM

    12697439 Trends in immunology , 2003 April: 24 (4 ) 158-61

  • Tryptase, a novel link between allergic inflammation and fibrosis.

    Levi-Schaffer F, Piliponsky AM

    12697439 Trends in immunology , 2003 April: 24 (4 ) 158-61

  • Non-IgE-dependent activation of human lung- and cord blood-derived mast cells is induced by eosinophil major basic protein and modulated by the membrane form of stem cell factor.

    Piliponsky AM, Gleich GJ, Nagler A, Bar I, Levi-Schaffer F

    12393403 Blood , 2003 Mar 1: 101 (5 ) 1898-904

  • Non-IgE-dependent activation of human lung- and cord blood-derived mast cells is induced by eosinophil major basic protein and modulated by the membrane form of stem cell factor.

    Piliponsky AM, Gleich GJ, Nagler A, Bar I, Levi-Schaffer F

    12393403 Blood , 2003 March: 101 (5 ) 1898-904

  • Mast cells as initiators and effectors of allergic inflammation. In: New Trends in Allergy V

    Solomon A, Piliponsky AM, Peer J, Levi-Schaffer F.

    (Ring J, Behrendt H, Eds.), Springer-Verlag Berlin, Heidelberg 2003. , 2003

  • Effects of eosinophils on mast cells: a new pathway for the perpetuation of allergic inflammation.

    Piliponsky AM, Gleich GJ, Bar I, Levi-Schaffer F

    12217410 Molecular immunology , 2002 Sept.: 38 (16-18 ) 1369

  • Effects of eosinophils on mast cells: a new pathway for the perpetuation of allergic inflammation.

    Piliponsky AM, Gleich GJ, Bar I, Levi-Schaffer F

    12217410 Molecular immunology , 2002 Sept.: 38 (16-18 ) 1369

  • Nerve growth factor and eosinophils in inflamed juvenile conjunctival nevus.

    Levi-Schaffer F, Micera A, Zamir E, Mechoulam H, Puxeddu I, Piliponsky AM, Aloe L, Pe'er J

    12036989 Investigative ophthalmology & visual science , 2002 June: 43 (6 ) 1850-6

  • Nerve growth factor and eosinophils in inflamed juvenile conjunctival nevus.

    Levi-Schaffer F, Micera A, Zamir E, Mechoulam H, Puxeddu I, Piliponsky AM, Aloe L, Pe'er J

    12036989 Investigative ophthalmology & visual science , 2002 June: 43 (6 ) 1850-6

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